The use of DDT powder causes an imbalance in the ecosystem primarily due to its tendency to bioaccumulate in the food chain. As DDT is not easily broken down, it builds up in the fatty tissues of animals, leading to toxic levels in top predators. This is especially harmful to birds, where it causes thinning of eggshells and reduced reproductive success, disrupting predator-prey relationships.

Additionally, DDT affects non-target species, including beneficial insects and aquatic organisms, leading to declines in their populations. This can alter plant communities and harm the overall health of the ecosystem. DDT contamination can also affect soil and water quality, further impacting aquatic life and potentially harming human health.